COVID-19: a fourth dose of vaccine for over 80 years and most fragile

The measurement has been decided while contaminations go backwards. The Scientific Council calls on the Government to consider expansion than 65 years with risk factors.

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Olivier Véran, the Minister of Health, announced on Friday 11 March, having seized the High Authority of Health (HAS) on the interest of a fourth dose of VVID-19 vaccine. The body responsible for the health strategy should meet next week to stop a position. But the government did not wait. Prime Minister Jean Castex announced on Saturday, March 12, in an interview in Paris, the opening of this second reminder for people over 80 years old.

This category of population represents 4.1 million French. Among it, 3.1 million have already received three injections. From this Monday, coughing those whose reminder goes back more than three months will be able to make a new appointment. The Prime Minister adds that this measure will also be recommended for “immunocompromised that were not eligible so far”. The tens of thousands of people whose most degraded immune system already had access to a fourth or even a fifth dose. Several hundred thousand extra people will be able to join them.

This unexpected announcement in its tempo does not hold chance. If the has had not yet expressed on the subject, the government had two other advice of expert authorities. On February 18, the Vaccine Strategy Guidance Board (COSV), set up on the occasion of this pandemic, had awarded an addendum to its previous notice, rendered a month earlier. While in January, he reserved the administration of a fourth dose to the great immunocompromised, he amended his position and “advocated the injection of a second vaccinal reminder for people over the age of 80 as well as resident. in EHPAD “.

” Low or no immune memory “

The COSV supported its flip-flop on four observations. He first saw an increase in admissions to critical care hospital over 80 who received their first recall, unlike other age classes. “This suggests that the protection against serious forms conferred in seniors by a reminder would diminish over time,” he said. A decrease that could be explained both by “a lower diversity of the antibodies generated by the vaccine and by a” answer T “, the second line of immune defense,” less effective in the context of a senestic immune memory ” .

This explanation feeds on a second series of data. France, they “suggest that people over 80 years old would have little or no immune memory as a result of anti-Covid-19 vaccination, as opposed to the lower classes,” says COSV. “These people are therefore dependent on a frequent reminder practice in order to maintain good immunity,” he continues.

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/Media reports.