For the first time in the history of mankind, doctors have successfully transplanted a whole eye along with part of the face. Aaron James was the patient who made history by undergoing this groundbreaking procedure. A year after the unique operation carried out in May 2023, doctors are pleased to report that the man’s condition is stable and the transplanted eyes have taken root.
The story of Aaron James began with a tragedy when he suffered a severe electric shock during work, causing significant damage to the left side of his body and face, including the eye. Initially, doctors planned for a partial skin transplant, but eventually decided on the unprecedented step of performing a whole eyeball transplantation.
Doctors from NYU Langone Health published a detailed report on the operation and the subsequent progress of the patient in the Jama magazine.
The 21-hour operation was meticulously planned and executed by surgeons, led by Dr. Daniel Cheradinini. The key challenge was the restoration of blood supply to the eye due to the intricate network of blood vessels and nerves in the area. To improve the odds of success, the doctors incorporated stem cells from the donor into the visual nerve.
One year later, doctors remain cautiously optimistic about the results. Although Aaron James has not regained vision in the transplanted eye, there is recorded electrical activity in the retina, indicating potential progress. The eye continues to receive adequate blood supply and remains stable in terms of size and pressure.
To prevent rejection, James is taking immunosuppressive drugs similar to those used by patients undergoing other organ transplants.
The aesthetic outcome of the procedure is particularly gratifying to the doctors. Dr. Cheradinini notes a significant improvement in Aaron’s appearance, which has had a positive impact on his life and allowed him to resume normal activities. Aaron expresses gratitude for the second chance he has been given and acknowledges the vital role played by the scientists and the donor in his recovery.
Despite the success of the transplantation, researchers acknowledge that not all cells of the transplanted eye survived. This highlights the need for continued improvement in the methodology of such procedures. Dr. Cheradinini emphasizes the importance of interdisciplinary collaboration among ophthalmologists, transplantologists, and plastic surgeons for the future success of similar operations. He hopes that his team’s achievement will inspire further research and advancements in this field globally.