Finnish scientists have identified a genetic link between depression and cardiovascular diseases (SVD), discovering a module of 256 genes that correlates with both conditions. The detection of this module paves the way for the development of new treatment methods aimed at combating both diseases simultaneously.
A study conducted at the University of Tampere in Finland revealed that certain genes may play a crucial role in the development of both depression and SVD. The researchers analyzed the genetic profiles of individuals with depression and SVD, identifying 256 genes in a single module. The expression of these genes at high or low levels increases the risk of both diseases.
The data used in the study were collected as part of the “Research of Young Finns” project that began in 1980 and involved over 3,500 children and adolescents. Participants were monitored regularly for more than 40 years, providing valuable insights into the development of diseases from childhood to adulthood.
Among all the genetic modules analyzed, one module named “Darkred” stood out. This module contained the 256 genes mentioned earlier and showed a significant correlation with both SVD metrics and the BDI-II depression evaluation scale, confirming the relationship between depression and SVD.
Past studies have highlighted the connection between depression and SVD, indicating that individuals with depression are more likely to experience cardiovascular issues, and vice versa. However, this recent study establishes a genetic link between both conditions, offering new possibilities for diagnosis and treatment strategies targeting both diseases.
This discovery not only reinforces existing knowledge about the relationship between depression and SVD but also presents new opportunities for medicine in combating these prevalent diseases. It promises more effective approaches to treatment and prevention in the future.