Researchers from the United States have developed two candidate vaccines that do not require low temperatures when stored and transport. Article of scientists is published in Journal of the American Chemical Society.
The first of the vaccine is based on the virus mosaic of cow peas, the second is on the bacteriophage of Q-beta. Researchers from the University of California in San Diego raised millions of their copies in the form of a nanoparticle of a spherical form. Then scientists collected these nanoparticles and attached an epitope to their surface – a small part of SARS-COV-2 S-COV-2, which is recognized by the immune system. The final product is not infected, but it allows the immunity to launch the production of neutralizing antibodies.
Such vaccines, emphasize researchers, inexpensive and easy to produce, and most importantly – remain resistant at high temperatures. As a result, they do not require a “cold chain” – a system of specialized storage and transportation at low temperatures. Resistance to the heat allowed researchers to “pack” vaccines into polymer implants and patches with micropholes. The manufacturing process took place at temperatures exceeding 100 degrees Celsius.
It is noted that this feature will allow people to choose the type of vaccination. The implants introduced under the skin will produce small doses of the vaccine within a month. Patches with micropigines glued on the skin will allow people to vaccinate themselves, without the presence of a doctor.
In the course of mice studies, drugs caused high production of neutralizing antibodies against SARS-COV-2.