UK scientists and India called the substance necessary for normal heart work. It turned out that adiponectin is a hormone produced by white adipose tissue, is able to compensate for the genetic predisposition to cardiovascular diseases. Specialists who have published an article in Plos One magazine have come to this conclusion.
The study was attended by 1886 Indians who had a high risk of developing diseases of the circulatory system. Such indicators as the body mass index, the level of blood sugar in an empty stomach and cholesterol were evaluated. It turned out that those who had cardiometabolic disorders (more than 80 percent of participants), there are low concentrations of adiponectin in the blood. This connection remained a clear even when taking into account third-party factors that usually affect heart health.
Further analysis showed that the level of adiponectin may decline in people with genetic variations in the production of Omhethine. Odenitine is secreted by visceral adipose tissue and enhances insulin sensitivity during normal weight, which has a beneficial effect on heart health. However, those who have the production of omensions reduced due to genetic features, cardiovascular diseases may develop even in the absence of excess weight.
According to scientists, improving the level of adiponectin in the body can be an effective strategy for maintaining heart health. Several previous studies have shown that weight loss in combination with diet and physical exercises can increase the level of adiponectin in plasma, while smoking and increasing the activity of the sympathetic nervous system usually reduce adiponectin concentration. Also, adiponectin can be enhanced by a number of drugs, including hypogle agents, PPAR-gamma agonists, and -alf receptors and radi-angiotensin system blockers.